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Neurochemical, histological, and behavioral profiling of the acute, sub‐acute, and chronic MPTP mouse model of Parkinsonʼs disease

Parkinson's disease (PD) is a heterogeneous multi‐systemic disorder unique to humans characterized by motor and non‐motor symptoms. Preclinical experimental models of PD present limitations and inconsistent neurochemical, histological, and behavioral readouts. The 1‐methyl‐4‐phenyl‐1,2,3,6‐tetr...

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Detalles Bibliográficos
Autores principales: Santoro, Matteo, Fadda, Paola, Klephan, Katie J., Hull, Claire, Teismann, Peter, Platt, Bettina, Riedel, Gernot
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10098710/
https://www.ncbi.nlm.nih.gov/pubmed/36184945
http://dx.doi.org/10.1111/jnc.15699