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Imaging of K(Ca)3.1 Channels in Tumor Cells with PET and Small‐Molecule Fluorescent Probes

The Ca(2+) activated K(+) channel K(Ca)3.1 is overexpressed in several human tumor cell lines, e. g. clear cell renal carcinoma, prostate cancer, non‐small cell lung cancer. Highly aggressive cancer cells use this ion channel for key processes of the metastatic cascade such as migration, extravasati...

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Detalles Bibliográficos
Autores principales: Thale, Insa, Maskri, Sarah, Grey, Lucie, Todesca, Luca Matteo, Budde, Thomas, Maisuls, Ivan, Strassert, Cristian A., Koch, Oliver, Schwab, Albrecht, Wünsch, Bernhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10098740/
https://www.ncbi.nlm.nih.gov/pubmed/36315933
http://dx.doi.org/10.1002/cmdc.202200551