Imidazolylpyrrolone‐Based Small Molecules as Anticancer Agents for Renal Cell Carcinoma

An in silico study focused on known cancer‐related target proteins, identified a selection of imidazo[4,5‐b]pyrrolo[3,4‐d]pyridines as potentially active. These compounds were prepared by a novel synthetic approach, designed and developed in‐house, based on the reaction of 5‐amino‐4‐cyanoformimidoyl...

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Detalles Bibliográficos
Autores principales: Sousa, Ana, Pontes, Olívia, Andrade, Juliana, Baltazar, Fátima, Costa, Marta, Proença, Fernanda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10098907/
https://www.ncbi.nlm.nih.gov/pubmed/36310147
http://dx.doi.org/10.1002/cmdc.202200519

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10098907/
https://www.ncbi.nlm.nih.gov/pubmed/36310147
http://dx.doi.org/10.1002/cmdc.202200519

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