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Imidazolylpyrrolone‐Based Small Molecules as Anticancer Agents for Renal Cell Carcinoma
An in silico study focused on known cancer‐related target proteins, identified a selection of imidazo[4,5‐b]pyrrolo[3,4‐d]pyridines as potentially active. These compounds were prepared by a novel synthetic approach, designed and developed in‐house, based on the reaction of 5‐amino‐4‐cyanoformimidoyl...
Autores principales: | Sousa, Ana, Pontes, Olívia, Andrade, Juliana, Baltazar, Fátima, Costa, Marta, Proença, Fernanda |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10098907/ https://www.ncbi.nlm.nih.gov/pubmed/36310147 http://dx.doi.org/10.1002/cmdc.202200519 |
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