Evolutionary aspects of mutation in functional motif and post-translational modifications in SARS-CoV-2 3CLpro (Mpro): an in-silico study

SARS CoV-2 is the virus that caused the COVID-19 pandemic. The main protease is one of the most prominent pharmacological targets for developing anti-COVID-19 therapeutic drugs (Mpro); SARS-CoV-2 replication is dependent on this component. SARS CoV-2’s Mpro/cysteine protease is quite identical to SA...

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Detalles Bibliográficos
Autores principales: Gupta, Amit, Sahu, Niharika, Singh, Vinay Kumar, Sinha, Rajeshwar P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10099016/
https://www.ncbi.nlm.nih.gov/pubmed/37361001
http://dx.doi.org/10.1007/s42485-023-00105-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10099016/
https://www.ncbi.nlm.nih.gov/pubmed/37361001
http://dx.doi.org/10.1007/s42485-023-00105-9

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