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Evolutionary aspects of mutation in functional motif and post-translational modifications in SARS-CoV-2 3CLpro (Mpro): an in-silico study
SARS CoV-2 is the virus that caused the COVID-19 pandemic. The main protease is one of the most prominent pharmacological targets for developing anti-COVID-19 therapeutic drugs (Mpro); SARS-CoV-2 replication is dependent on this component. SARS CoV-2’s Mpro/cysteine protease is quite identical to SA...
Autores principales: | Gupta, Amit, Sahu, Niharika, Singh, Vinay Kumar, Sinha, Rajeshwar P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Nature Singapore
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10099016/ https://www.ncbi.nlm.nih.gov/pubmed/37361001 http://dx.doi.org/10.1007/s42485-023-00105-9 |
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