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Design and Synthesis of Covalent Inhibitors of FabA
[Image: see text] There is an urgent need for the development of new therapeutics with novel modes of action to target Gram-negative bacterial infections, due to resistance to current drugs. Previously, FabA, an enzyme in the bacterial type II fatty acid biosynthesis pathway, was identified as a pot...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10099128/ https://www.ncbi.nlm.nih.gov/pubmed/37065080 http://dx.doi.org/10.1021/acsomega.2c08031 |