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Sequence and Structural Motifs Controlling the Broad Substrate Specificity of the Mycobacterial Hormone-Sensitive Lipase LipN

[Image: see text] Mycobacterium tuberculosis has a complex life cycle transitioning between active and dormant growth states depending on environmental conditions. LipN (Rv2970c) is a conserved mycobacterial serine hydrolase with regulated catalytic activity at the interface between active and dorma...

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Detalles Bibliográficos
Autores principales: Schemenauer, Daniel E., Pool, Emily H., Raynor, Stephanie N., Ruiz, Gabriela P., Goehring, Leah M., Koelper, Andrew J., Wilson, Madeleine A., Durand, Anthony J., Kourtoglou, Elexi C., Larsen, Erik M., Lavis, Luke D., Esteb, John J., Hoops, Geoffrey C., Johnson, R. Jeremy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10099132/
https://www.ncbi.nlm.nih.gov/pubmed/37065048
http://dx.doi.org/10.1021/acsomega.3c00534