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Identification of Novel Tau-Tubulin Kinase 2 Inhibitors Using Computational Approaches

[Image: see text] Tau tubulin kinase 2 (TTBK2) associated with multiple diseases is one of the kinases which phosphorylates tau and tubulin. Numerous efforts have been made to understand the role of TTBK2 in protein folding mechanisms and misfolding behavior. The misfolded protein intermediates form...

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Detalles Bibliográficos
Autores principales: Ahamad, Shahzaib, Hema, Kanipakam, Gupta, Dinesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10099139/
https://www.ncbi.nlm.nih.gov/pubmed/37065061
http://dx.doi.org/10.1021/acsomega.3c00225