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Discovery of Novel Dimeric Pyridinium Bromide Analogues Inhibits Cancer Cell Growth by Activating Caspases and Downregulating Bcl-2 Protein

[Image: see text] Flexible dimeric substituted pyridinium bromides with primary and tertiary amines are prepared by conventional and solvent-free methods. The formation of compounds 2 and 4 is much easier than that of compounds 1 and 3 because of the benzyl carbon which is more electropositive than...

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Detalles Bibliográficos
Autores principales: Govindaraj, Senthilnathan, Ganesan, Kilivelu, Dharmasivam, Mahendiran, Raman, Lakshmisundaram, Kuppusamy, Kalaivani M., Pandiappan, Viswanathan, Alam, Mohammed Mujahid, Mohammed, Amanullah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10099142/
https://www.ncbi.nlm.nih.gov/pubmed/37065022
http://dx.doi.org/10.1021/acsomega.3c00526