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Carba‐Sugar Analogs of Glucosamine‐6‐Phosphate: New Activators for the glmS Riboswitch

Riboswitches are 5’‐untranslated mRNA regions mostly found in bacteria. They are promising drug targets to overcome emerging bacterial resistance against commonly used antibiotics. The glmS riboswitch is unique among the family of riboswitches as it is a ribozyme that undergoes self‐cleavage upon bi...

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Detalles Bibliográficos
Autores principales: Stängle, David, Silkenath, Bjarne, Gehle, Paul, Esser, Anna, Mayer, Günter, Wittmann, Valentin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10099210/
https://www.ncbi.nlm.nih.gov/pubmed/36326082
http://dx.doi.org/10.1002/chem.202202378