Optimization of G‐Quadruplex Ligands through a SAR Study Combining Parallel Synthesis and Screening of Cationic Bis(acylhydrazones)

G‐quadruplexes (G4s), secondary structures adopted by guanine‐rich DNA and RNA sequences, are implicated in numerous biological processes and have been suggested as potential drug targets. Accordingly, there is an increasing interest in developing high‐throughput methods that allow the generation of...

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Detalles Bibliográficos
Autores principales: Reznichenko, Oksana, Leclercq, Denis, Franco Pinto, Jaime, Mouawad, Liliane, Gabelica, Valérie, Granzhan, Anton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10099395/
https://www.ncbi.nlm.nih.gov/pubmed/36286608
http://dx.doi.org/10.1002/chem.202202427

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10099395/
https://www.ncbi.nlm.nih.gov/pubmed/36286608
http://dx.doi.org/10.1002/chem.202202427

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