Preferential Solvation Study of Rosuvastatin in the {PEG400 (1) + Water (2)} Cosolvent Mixture and GastroPlus Software-Based In Vivo Predictions

[Image: see text] Rosuvastatin (RST) is a poorly water-soluble drug responsible for limited in vivo dissolution and subsequently low oral systemic absorption (poor bioavailability). The mole fraction solubility values of RST in various ratios of binary mixtures “{PEG400 (1) + water (2)}” at 298.15 K...

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Detalles Bibliográficos
Autores principales: Hussain, Afzal, Afzal, Obaid, Yasmin, Sabina, Haider, Nazima, Altamimi, Abdulmalik Saleh Alfawaz, Martinez, Fleming, Acree, William E., Ramzan, Mohhammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10099431/
https://www.ncbi.nlm.nih.gov/pubmed/37065087
http://dx.doi.org/10.1021/acsomega.2c07968

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10099431/
https://www.ncbi.nlm.nih.gov/pubmed/37065087
http://dx.doi.org/10.1021/acsomega.2c07968

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