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To Explore the Binding Affinity of Human γ-Secretase Activating Protein (GSAP) Isoform 4 with APP-C99 Peptides

[Image: see text] γ-Secretase activating protein (GSAP) is known to play an important role in the β-amyloid pathway. It acts as a modulator and accentuates the truncation of the amyloid precursor protein C-99 fragment through the γ-secretase complex. GSAP has four isoforms, out of which canonical is...

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Detalles Bibliográficos
Autores principales: Angira, Deekshi, Chaudhary, Sonali, Abiramasundari, Arumugam, Thiruvenkatam, Vijay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10099435/
https://www.ncbi.nlm.nih.gov/pubmed/37065030
http://dx.doi.org/10.1021/acsomega.3c01117