Gene targeting as a therapeutic avenue in diseases mediated by the complement alternative pathway

The complement alternative pathway (AP) is implicated in numerous diseases affecting many organs, ranging from the rare hematological disease paroxysmal nocturnal hemoglobinuria (PNH), to the common blinding disease age‐related macular degeneration (AMD). Critically, the AP amplifies any activating...

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Detalles Bibliográficos
Autores principales: Dreismann, Anna K, Hallam, Thomas M, Tam, Lawrence CS, Nguyen, Calvin V, Hughes, Jane P, Ellis, Scott, Harris, Claire L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Invited Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10099504/
https://www.ncbi.nlm.nih.gov/pubmed/36369963
http://dx.doi.org/10.1111/imr.13149

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10099504/
https://www.ncbi.nlm.nih.gov/pubmed/36369963
http://dx.doi.org/10.1111/imr.13149

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