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Accelerated and Concerted Aza‐Michael Addition and SuFEx Reaction in Microdroplets in Unitary and High‐Throughput Formats
The sulfur fluoride exchange (SuFEx) reaction is significant in drug discovery, materials science, and chemical biology. Conventionally, it involves installation of SO(2)F followed by fluoride exchange by a catalyst. We report catalyst‐free Aza‐Michael addition to install SO(2)F and then SuFEx react...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10099520/ https://www.ncbi.nlm.nih.gov/pubmed/36253886 http://dx.doi.org/10.1002/anie.202214090 |