Multiplexed cellular profiling identifies an organoselenium compound as an inhibitor of CRM1‐mediated nuclear export

Chromosomal region maintenance 1 (CRM1 also known as Xpo1 and exportin‐1) is the receptor for the nuclear export controlling the intracellular localization and function of many cellular and viral proteins that play a crucial role in viral infections and cancer. The inhibition of CRM1 has emerged as...

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Detalles Bibliográficos
Autores principales: Jimenez, Lucia, Mayoral‐Varo, Victor, Amenábar, Carlos, Ortega, Judit, Sequeira, João G. N., Machuqueiro, Miguel, Mourato, Cristiana, Silvestri, Romano, Angeli, Andrea, Carta, Fabrizio, Supuran, Claudiu T., Megías, Diego, Ferreira, Bibiana I., Link, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons A/S 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10099545/
https://www.ncbi.nlm.nih.gov/pubmed/36353954
http://dx.doi.org/10.1111/tra.12872

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10099545/
https://www.ncbi.nlm.nih.gov/pubmed/36353954
http://dx.doi.org/10.1111/tra.12872

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