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Resistance to energy metabolism - targeted therapy of AML cells residual in the bone marrow microenvironment

In response to the changing availability of nutrients and oxygen in the bone marrow microenvironment, acute myeloid leukemia (AML) cells continuously adjust their metabolic state. To meet the biochemical demands of their increased proliferation, AML cells strongly depend on mitochondrial oxidative p...

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Detalles Bibliográficos
Autores principales: Tabe, Yoko, Konopleva, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: OAE Publishing Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10099600/
https://www.ncbi.nlm.nih.gov/pubmed/37065866
http://dx.doi.org/10.20517/cdr.2022.133