Serendipitous Identification of a Covalent Activator of Liver Pyruvate Kinase

Enzymes are effective biological catalysts that accelerate almost all metabolic reactions in living organisms. Synthetic modulators of enzymes are useful tools for the study of enzymatic reactions and can provide starting points for the design of new drugs. Here, we report on the discovery of a clas...

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Detalles Bibliográficos
Autores principales: Battisti, Umberto Maria, Gao, Chunxia, Nilsson, Oscar, Akladios, Fady, Lulla, Aleksei, Bogucka, Agnieszka, Nain‐Perez, Amalyn, Håversen, Liliana, Kim, Woonghee, Boren, Jan, Hyvönen, Marko, Uhlen, Mathias, Mardinoglu, Adil, Grøtli, Morten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10099687/
https://www.ncbi.nlm.nih.gov/pubmed/36250581
http://dx.doi.org/10.1002/cbic.202200339

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10099687/
https://www.ncbi.nlm.nih.gov/pubmed/36250581
http://dx.doi.org/10.1002/cbic.202200339

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