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A Novel Subgroup of UCHL1-Related Cancers Is Associated with Genomic Instability and Sensitivity to DNA-Damaging Treatment

SIMPLE SUMMARY: In this study, a new subgroup of UCHL1-related cancers was identified across multiple solid tumor entities and was characterized by comprehensive multi-omics analysis. Common features of UCHL1-related cancers are an increased genomic instability and a vulnerability to DNA-damaging tr...

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Detalles Bibliográficos
Autores principales: Burkart, Sebastian, Weusthof, Christopher, Khorani, Karam, Steen, Sonja, Stögbauer, Fabian, Unger, Kristian, Hess, Julia, Zitzelsberger, Horst, Belka, Claus, Kurth, Ina, Hess, Jochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10099714/
https://www.ncbi.nlm.nih.gov/pubmed/36980544
http://dx.doi.org/10.3390/cancers15061655