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Chemical Proteomics Reveals Protein Tyrosination Extends Beyond the Alpha‐Tubulins in Human Cells

Tubulin detyrosination‐tyrosination cycle regulates the stability of microtubules. With respect to α‐tubulins, the tyrosination level is maintained by a single tubulin‐tyrosine ligase (TTL). However, the precise dynamics and tubulin isoforms which undergo (de)tyrosination in neurons are unknown. Her...

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Detalles Bibliográficos
Autores principales: Makarov, Dmytro, Kielkowski, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10099736/
https://www.ncbi.nlm.nih.gov/pubmed/36218090
http://dx.doi.org/10.1002/cbic.202200414