Highly Cytotoxic Molybdenocenes with Strong Metabolic Effects Inhibit Tumour Growth in Mice

A series of six highly lipophilic Cp‐substituted molybdenocenes bearing different bioactive chelating ligands was synthesized and characterized by NMR spectroscopy, mass spectrometry and X‐ray crystallography. In vitro experiments showed a greatly increased cytotoxic potency when compared to the non...

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Detalles Bibliográficos
Autores principales: Fuchs, Valentin, Cseh, Klaudia, Hejl, Michaela, Vician, Petra, Neuditschko, Benjamin, Meier‐Menches, Samuel M., Janker, Lukas, Bileck, Andrea, Gajic, Natalie, Kronberger, Julia, Schaier, Martin, Neumayer, Sophie, Köllensperger, Gunda, Gerner, Christopher, Berger, Walter, Jakupec, Michael A., Malarek, Michael S., Keppler, Bernhard K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10099754/
https://www.ncbi.nlm.nih.gov/pubmed/36222279
http://dx.doi.org/10.1002/chem.202202648

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10099754/
https://www.ncbi.nlm.nih.gov/pubmed/36222279
http://dx.doi.org/10.1002/chem.202202648

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