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Highly Cytotoxic Molybdenocenes with Strong Metabolic Effects Inhibit Tumour Growth in Mice
A series of six highly lipophilic Cp‐substituted molybdenocenes bearing different bioactive chelating ligands was synthesized and characterized by NMR spectroscopy, mass spectrometry and X‐ray crystallography. In vitro experiments showed a greatly increased cytotoxic potency when compared to the non...
Autores principales: | Fuchs, Valentin, Cseh, Klaudia, Hejl, Michaela, Vician, Petra, Neuditschko, Benjamin, Meier‐Menches, Samuel M., Janker, Lukas, Bileck, Andrea, Gajic, Natalie, Kronberger, Julia, Schaier, Martin, Neumayer, Sophie, Köllensperger, Gunda, Gerner, Christopher, Berger, Walter, Jakupec, Michael A., Malarek, Michael S., Keppler, Bernhard K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10099754/ https://www.ncbi.nlm.nih.gov/pubmed/36222279 http://dx.doi.org/10.1002/chem.202202648 |
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