Cargando…

The Integration of Proteome-Wide PTM Data with Protein Structural and Sequence Features Identifies Phosphorylations that Mediate 14-3-3 Interactions

14-3-3s are abundant proteins that regulate essentially all aspects of cell biology, including cell cycle, motility, metabolism, and cell death. 14-3-3s work by docking to phosphorylated Ser/Thr residues on a large network of client proteins and modulating client protein function in a variety of way...

Descripción completa

Detalles Bibliográficos
Autores principales: Egbert, C. M., Warr, L. R., Pennington, K. L., Thornton, M. M., Vaughan, A. J., Ashworth, S. W., Heaton, M. J., English, N., Torres, M. P., Andersen, J. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10099770/
https://www.ncbi.nlm.nih.gov/pubmed/36402225
http://dx.doi.org/10.1016/j.jmb.2022.167890