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Interactive Bioconjugation at N‐Terminal Cysteines by Using O‐Salicylaldehyde Esters towards Dual Site‐Selective Functionalization

N‐terminal Cys modification has been intensively studied to produce homogeneous bioconjugates essentially through two modes of reaction: reversible modification with the equilibrium shifted towards the formation of the desired conjugate or stable and irreversible conjugates. Herein, we report a new...

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Detalles Bibliográficos
Autores principales: Silva, Maria J. S. A., Cavadas, Rafaela A. N., Faustino, Hélio, Veiros, Luís F., Gois, Pedro M. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10099860/
https://www.ncbi.nlm.nih.gov/pubmed/36245264
http://dx.doi.org/10.1002/chem.202202377