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Examination of epigenetic inhibitor zebularine in treatment of skin wounds in healthy and diabetic mice

DNA methyltransferase inhibitor zebularine was proven to induce regeneration in the ear pinna in mice. We utilized a dorsal skin wound model to further evaluate this epigenetic inhibitor in wound healing. Full‐thickness excisional wounds were made on the dorsum of 2 and 10‐month‐old healthy BALB/c a...

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Detalles Bibliográficos
Autores principales: Sass, Piotr, Sosnowski, Paweł, Kamińska, Jolanta, Deptuła, Milena, Skoniecka, Aneta, Zieliński, Jacek, Rodziewicz‐Motowidło, Sylwia, Pikuła, Michał, Sachadyn, Paweł
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10099879/
https://www.ncbi.nlm.nih.gov/pubmed/36350668
http://dx.doi.org/10.1002/term.3365