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Development of a micronucleus test using the EpiAirway™ organotypic human airway model

BACKGROUND: The use of organotypic human tissue models in genotoxicity has increased as an alternative to animal testing. Genotoxicity is generally examined using a battery of in vitro assays such as Ames and micronucleus (MN) tests that cover gene mutations and structural and numerical chromosome a...

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Detalles Bibliográficos
Autores principales: Munakata, Satoru, Watanabe, Taku, Takahashi, Tomohiro, Kimuro, Shiori, Ishimori, Kanae, Hashizume, Tsuneo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10099928/
https://www.ncbi.nlm.nih.gov/pubmed/37046355
http://dx.doi.org/10.1186/s41021-023-00269-2