Cargando…

Development of a micronucleus test using the EpiAirway™ organotypic human airway model

BACKGROUND: The use of organotypic human tissue models in genotoxicity has increased as an alternative to animal testing. Genotoxicity is generally examined using a battery of in vitro assays such as Ames and micronucleus (MN) tests that cover gene mutations and structural and numerical chromosome a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Munakata, Satoru, Watanabe, Taku, Takahashi, Tomohiro, Kimuro, Shiori, Ishimori, Kanae, Hashizume, Tsuneo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10099928/ https://www.ncbi.nlm.nih.gov/pubmed/37046355 http://dx.doi.org/10.1186/s41021-023-00269-2

Ejemplares similares

Prevalidation of an Acute Inhalation Toxicity Test Using the EpiAirway In Vitro Human Airway Model
por: Jackson, George R., et al.
Publicado: (2018)

Characterization of ABC Transporters in EpiAirway™, a Cellular Model of Normal Human Bronchial Epithelium
por: Rotoli, Bianca Maria, et al.
Publicado: (2020)

Organic Cation Transporters (OCTs) in EpiAirway™, a Cellular Model of Normal Human Bronchial Epithelium
por: Barilli, Amelia, et al.
Publicado: (2020)

In vitro acute inhalation toxicity for TiO(2) (GST) using 3D human tissue model (EpiAirway(™))
por: Jang, Seong Yong, et al.
Publicado: (2021)

A synthetic coolant (WS-23) in disposable electronic cigarettes impairs cytoskeletal function in EpiAirway microtissues exposed at the air liquid interface
por: Wong, Man, et al.
Publicado: (2023)

Evaluation of in vitro Penetration of Fluticasone Propionate from MP-AzeFlu and Fluticasone Propionate Nasal Spray Through EpiAirway™606 Tissues Using Vertical Diffusion Cells
por: Berger, William E, et al.
Publicado: (2020)

Biologic Impact of Green Synthetized Magnetic Iron Oxide Nanoparticles on Two Different Lung Tumorigenic Monolayers and a 3D Normal Bronchial Model—EpiAirway(TM) Microtissue
por: Moacă, Elena-Alina, et al.
Publicado: (2022)

ACE2 Expression in Organotypic Human Airway Epithelial Cultures and Airway Biopsies
por: Chen, Qianyu, et al.
Publicado: (2022)

Mass production of human airway-like neutrophils via transmigration in an organotypic model of human airways
por: Dobosh, Brian, et al.
Publicado: (2021)

Organotypic sinonasal airway culture systems are predictive of the mucociliary phenotype produced by bronchial airway epithelial cells
por: Delhove, Juliette, et al.
Publicado: (2022)

Effects of repeated cigarette smoke extract exposure over one month on human bronchial epithelial organotypic culture
por: Ito, Shigeaki, et al.
Publicado: (2018)

Non-Polio Enterovirus C Replicate in Both Airway and Intestine Organotypic Cultures
por: Moreni, Giulia, et al.
Publicado: (2023)

Use of the EpiDerm(TM) 3D reconstructed skin micronucleus assay for fragrance materials
por: Thakkar, Yax, et al.
Publicado: (2021)

In vitro long‐term repeated exposure and exposure switching of a novel tobacco vapor product in a human organotypic culture of bronchial epithelial cells
por: Ito, Shigeaki, et al.
Publicado: (2020)

A 3D epithelial–mesenchymal co-culture model of human bronchial tissue recapitulates multiple features of airway tissue remodeling by TGF-β1 treatment
por: Ishikawa, Shinkichi, et al.
Publicado: (2017)

Multimorbidity clusters in patients with chronic obstructive airway diseases in the EpiChron Cohort
por: Carmona-Pírez, Jonás, et al.
Publicado: (2021)

The “epiTet” of Air Pollution: Epigenetic Regulation of Airway Inflammation by Tet1
por: Ji, Hong, et al.
Publicado: (2023)

The micronucleus test as an in vivo cytogenetic method.
por: Miller, R C
Publicado: (1973)

Characterizing the extracellular vesicle proteomic landscape of the human airway using in vitro organotypic multi-cellular models
por: Vitucci, Eva C.M., et al.
Publicado: (2023)

Genetic toxicity testing using human in vitro organotypic airway cultures: Assessing DNA damage with the CometChip and mutagenesis by Duplex Sequencing
por: Wang, Yiying, et al.
Publicado: (2021)

The use of the Sanuki airway™ in three patients with suspected difficult airway
por: Kuwana, Keisuke, et al.
Publicado: (2021)

Cytotoxicity of Mouthrinses on Epithelial Cells by Micronucleus Test
por: Erdemir, Ebru Olgun, et al.
Publicado: (2007)

The micronucleus test—most widely used in vivo genotoxicity test—
por: Hayashi, Makoto
Publicado: (2016)

Detecting Alterations in Pulmonary Airway Development with Airway-by-Airway Comparison
por: Lee, DongYoub, et al.
Publicado: (2011)

Airway in the Airway
por: Sharma, Ankur, et al.
Publicado: (2021)

Automation and validation of micronucleus detection in the 3D EpiDerm™ human reconstructed skin assay and correlation with 2D dose responses
por: Chapman, K. E., et al.
Publicado: (2014)

ECVAM retrospective validation of in vitro micronucleus test (MNT)
por: Corvi, Raffaella, et al.
Publicado: (2008)

Lack of genotoxicity of rhubarb (rhizome) in the Ames and micronucleus in vitro tests
por: Melzi, Gloria, et al.
Publicado: (2022)

Micronucleus Assay: Pitfalls and Challenges
por: Naderi, Noushin Jalayer
Publicado: (2020)

Protective barrier properties of Rhinosectan(®) spray (containing xyloglucan) on an organotypic 3D airway tissue model (MucilAir): results of an in vitro study
por: De Servi, Barbara, et al.
Publicado: (2017)

Invited review: human air-liquid-interface organotypic airway tissue models derived from primary tracheobronchial epithelial cells—overview and perspectives
por: Cao, Xuefei, et al.
Publicado: (2020)

Human Organotypic Airway and Lung Organoid Cells of Bronchiolar and Alveolar Differentiation Are Permissive to Infection by Influenza and SARS-CoV-2 Respiratory Virus
por: Ekanger, Camilla Tvedt, et al.
Publicado: (2022)

Application of cell sorting for enhancing the performance of the cytokinesis-block micronucleus assay
por: Nakamura, Ayumi, et al.
Publicado: (2016)

Disruption of airway lymphatics as a novel cause of impairment of airway clearance in severe asthma
por: Ebina, Masahito, et al.
Publicado: (2013)

Association between cervical lesion grade and micronucleus frequency in the Papanicolaou test
por: Bueno, Caroline Tanski, et al.
Publicado: (2014)

Genotoxicity Evaluation of Capsaicin-Containing (CP) Pharmacopuncture, in an In Vivo Micronucleus Test
por: Hwang, Ji Hye, et al.
Publicado: (2020)

Vicia–Micronucleus Test Application for Saline Irrigation Water Risk Assessment
por: Souguir, Dalila, et al.
Publicado: (2022)

Micronucleus test using formalin-fixed rat glandular stomach and colon
por: Ohyama, Wakako, et al.
Publicado: (2023)

Regulation of Airway Smooth Muscle Cell Proliferation by Diacylglycerol Kinase: Relevance to Airway Remodeling in Asthma
por: Hernandez-Lara, Miguel Angel, et al.
Publicado: (2022)

EPI test in West Hall
Publicado: (1977)

Cannot write session to /tmp/vufind_sessions/sess_7i5c3mfsbssthbch319kkqga6u