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Combined utility of p16 and BRAF V600E in the evaluation of spitzoid tumors: Superiority to PRAME and correlation with FISH

BACKGROUND: Spitzoid melanocytic neoplasms are diagnostically challenging; criteria for malignancy continue to evolve. The ability to predict chromosomal abnormalities with immunohistochemistry (IHC) could help select cases requiring chromosomal evaluation. METHODS: Fluorescence in situ hybridizatio...

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Detalles Bibliográficos
Autores principales: McAfee, John L., Scarborough, Richard, Jia, Xuefei Sophia, Azzato, Elizabeth M., Astbury, Caroline, Ronen, Shira, Andea, Aleodor A., Billings, Steven D., Ko, Jennifer S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10099989/
https://www.ncbi.nlm.nih.gov/pubmed/36261329
http://dx.doi.org/10.1111/cup.14342