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Cannabinoid 1 (CB(1)) receptor arrestin subtype‐selectivity and phosphorylation dependence

BACKGROUND AND PURPOSE: Arrestin or G protein bias may be desirable for novel cannabinoid therapeutics. Arrestin‐2 and arrestin‐3 translocation to CB(1) receptor have been suggested to mediate different functions that may be exploited with biased ligands. Here, the requirement of a recently describe...

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Detalles Bibliográficos
Autores principales: Manning, Jamie J., Rawcliffe, Gabriel, Finlay, David B., Glass, Michelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10100024/
https://www.ncbi.nlm.nih.gov/pubmed/36250246
http://dx.doi.org/10.1111/bph.15973