Boroleucine‐Derived Covalent Inhibitors of the ZIKV Protease

The Zika virus (ZIKV) remains a potential threat to the public health due to the lack of both an approved vaccination or a specific treatment. In this work, a series of peptidic inhibitors of the ZIKV protease with boroleucine as P1 residue was synthesized. The highest affinities with K (i) values d...

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Detalles Bibliográficos
Autores principales: Braun, Niklas J., Huber, Simon, Schmacke, Luna C., Heine, Andreas, Steinmetzer, Torsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10100045/
https://www.ncbi.nlm.nih.gov/pubmed/36325810
http://dx.doi.org/10.1002/cmdc.202200336

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10100045/
https://www.ncbi.nlm.nih.gov/pubmed/36325810
http://dx.doi.org/10.1002/cmdc.202200336

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