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A thrombophilic allele of clotting Factor VII/VIIa promoting recurrent pulmonary emboli, clinical details, and a structural model of the altered protein: a case report

BACKGROUND: The clotting or hemostasis system is a meticulously regulated set of enzymatic reactions that occur in the blood and culminate in formation of a fibrin clot. The precisely calibrated signaling system that prevents or initiates clotting originates with the activated Factor Seven (FVIIa) c...

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Detalles Bibliográficos
Autores principales: Newman, Kenneth, Daldal, Fevzi, Dancis, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10100170/
https://www.ncbi.nlm.nih.gov/pubmed/37055848
http://dx.doi.org/10.1186/s13256-023-03833-0