Defining the Biologically Plausible Taxonomic Domain of Applicability of an Adverse Outcome Pathway: A Case Study Linking Nicotinic Acetylcholine Receptor Activation to Colony Death

For the majority of developed adverse outcome pathways (AOPs), the taxonomic domain of applicability (tDOA) is typically narrowly defined with a single or a handful of species. Defining the tDOA of an AOP is critical for use in regulatory decision‐making, particularly when considering protection of...

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Detalles Bibliográficos
Autores principales: Jensen, Marissa A., Blatz, Donovan J., LaLone, Carlie A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Environmental Toxicology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10100214/
https://www.ncbi.nlm.nih.gov/pubmed/36263952
http://dx.doi.org/10.1002/etc.5501

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10100214/
https://www.ncbi.nlm.nih.gov/pubmed/36263952
http://dx.doi.org/10.1002/etc.5501

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