Investigating the Active Oxidants Involved in Cytochrome P450 Catalyzed Sulfoxidation Reactions

Cytochrome P450 (CYP) heme‐thiolate monooxygenases catalyze the hydroxylation of the C−H bonds of organic molecules. This reaction is initiated by a ferryl‐oxo heme radical cation (Cpd I). These enzymes can also catalyze sulfoxidation reactions and the ferric‐hydroperoxy complex (Cpd 0) and the Fe(I...

Descripción completa

Detalles Bibliográficos
Autores principales: Podgorski, Matthew N., Coleman, Tom, Churchman, Luke R., Bruning, John B., De Voss, James J., Bell, Stephen G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10100219/
https://www.ncbi.nlm.nih.gov/pubmed/36169207
http://dx.doi.org/10.1002/chem.202202428

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10100219/
https://www.ncbi.nlm.nih.gov/pubmed/36169207
http://dx.doi.org/10.1002/chem.202202428

Ejemplares similares