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In Vivo Biocatalytic Cascades Featuring an Artificial‐Enzyme‐Catalysed New‐to‐Nature Reaction

Artificial enzymes utilizing the genetically encoded non‐proteinogenic amino acid p‐aminophenylalanine (pAF) as a catalytic residue are able to react with carbonyl compounds through an iminium ion mechanism to promote reactions that have no equivalent in nature. Herein, we report an in vivo biocatal...

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Detalles Bibliográficos
Autores principales: Ofori Atta, Linda, Zhou, Zhi, Roelfes, Gerard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10100225/
https://www.ncbi.nlm.nih.gov/pubmed/36342952
http://dx.doi.org/10.1002/anie.202214191