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Inhibition of NLRP1 inflammasome improves autophagy dysfunction and Aβ disposition in APP/PS1 mice

Increasing evidence has shown that the NOD-like receptor protein 1 (NLRP1) inflammasome is associated with Aβ generation and deposition, which contributes to neuronal damage and neuronal-inflammation in Alzheimer's disease (AD). However, the specific mechanism of NLRP1 inflammasome in the patho...

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Detalles Bibliográficos
Autores principales: Li, Xuewang, Zhang, Han, Yang, Liu, Dong, Xianan, Han, Yuli, Su, Yong, Li, Weiping, Li, Weizu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10100229/
https://www.ncbi.nlm.nih.gov/pubmed/37055801
http://dx.doi.org/10.1186/s12993-023-00209-8