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Inhibition of NLRP1 inflammasome improves autophagy dysfunction and Aβ disposition in APP/PS1 mice

Increasing evidence has shown that the NOD-like receptor protein 1 (NLRP1) inflammasome is associated with Aβ generation and deposition, which contributes to neuronal damage and neuronal-inflammation in Alzheimer's disease (AD). However, the specific mechanism of NLRP1 inflammasome in the patho...

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Detalles Bibliográficos
Autores principales:	Li, Xuewang, Zhang, Han, Yang, Liu, Dong, Xianan, Han, Yuli, Su, Yong, Li, Weiping, Li, Weizu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10100229/ https://www.ncbi.nlm.nih.gov/pubmed/37055801 http://dx.doi.org/10.1186/s12993-023-00209-8

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