Recurrent missense variants in clonal hematopoiesis‐related genes present in the general population

Clonal hematopoiesis (CH) consists in an abnormal expansion of a hematopoietic stem cell bearing an advantageous somatic variant. A survey of known recurrent somatic missense variants in DNMT3A, SF3B1, SRSF2, and TP53, some of the most prominent genes underlying CH of indeterminate potential (CHIP),...

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Detalles Bibliográficos
Autores principales: Ariste, Olivier, de la Grange, Pierre, Veitia, Reiner A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2022
Materias:
Short Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10100246/
https://www.ncbi.nlm.nih.gov/pubmed/36353970
http://dx.doi.org/10.1111/cge.14259

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10100246/
https://www.ncbi.nlm.nih.gov/pubmed/36353970
http://dx.doi.org/10.1111/cge.14259

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