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Re-thinking osteoarthritis pathogenesis: what can we learn (and what do we need to unlearn) from mouse models about the mechanisms involved in disease development

Efforts to develop effective disease-modifying drugs to treat osteoarthritis have so far proved unsuccessful with a number of promising drug candidates from pre-clinical studies failing to show efficacy in clinical trials. It is therefore timely to re-evaluate our current understanding of osteoarthr...

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Detalles Bibliográficos
Autores principales: Poulsen, Raewyn C., Jain, Lekha, Dalbeth, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10100340/
https://www.ncbi.nlm.nih.gov/pubmed/37046337
http://dx.doi.org/10.1186/s13075-023-03042-6