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Thiamyxins: Structure and Biosynthesis of Myxobacterial RNA‐Virus Inhibitors

During our search for novel myxobacterial natural products, we discovered the thiamyxins: thiazole‐ and thiazoline‐rich non‐ribosomal peptide‐polyketide hybrids with potent antiviral activity. We isolated four congeners of this unprecedented natural product family with the non‐cyclized thiamyxin D f...

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Detalles Bibliográficos
Autores principales: Haack, Patrick A., Harmrolfs, Kirsten, Bader, Chantal D., Garcia, Ronald, Gunesch, Antonia P., Haid, Sibylle, Popoff, Alexander, Voltz, Alexander, Kim, Heeyoung, Bartenschlager, Ralf, Pietschmann, Thomas, Müller, Rolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10100342/
https://www.ncbi.nlm.nih.gov/pubmed/36208117
http://dx.doi.org/10.1002/anie.202212946