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WY14643 Increases Herpesvirus Replication and Inhibits IFNβ Production Independently of PPARα Expression

Peroxisome proliferator activated receptor (PPAR) agonists are commonly used to treat metabolic disorders in humans because they regulate fatty acid oxidation and cholesterol metabolism. In addition to their roles in controlling metabolism, PPAR agonists also regulate inflammation and are immunosupp...

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Detalles Bibliográficos
Autores principales: Tao, Lili, Dryden, Phillip, Lowe, Alexandria, Wang, Guoxun, Achuthkumar, Amritha, Chang, Tyron, Reese, Tiffany A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10100363/
https://www.ncbi.nlm.nih.gov/pubmed/36715509
http://dx.doi.org/10.1128/spectrum.02337-22