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Clonal Changes in the Pneumococcal Population Carried by Portuguese Children during Six Years of Private Use of the 13-Valent Pneumococcal Conjugate Vaccine: the Relative Contribution of Clonal Expansion, Clonal Emergence, and Capsular Switch Events

In Portugal, the 13-valent pneumococcal conjugate vaccine (PCV13) was available for private use from 2010 to 2015 and it was introduced in the National Immunization Program in 2015. We have reported that private use of PCV13 led to extensive serotype replacement and an increase in antimicrobial susc...

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Detalles Bibliográficos
Autores principales: Candeias, Catarina, Félix, Sofia, Handem, Sara, de Lencastre, Hermínia, Sá-Leão, Raquel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10100364/
https://www.ncbi.nlm.nih.gov/pubmed/36946753
http://dx.doi.org/10.1128/spectrum.02909-22