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Clostridium butyricum and Chitooligosaccharides in Synbiotic Combination Ameliorate Symptoms in a DSS-Induced Ulcerative Colitis Mouse Model by Modulating Gut Microbiota and Enhancing Intestinal Barrier Function

Effects of Clostridium butyricum and chitooligosaccharides (COS), singly and in synbiotic combination, were evaluated in a C57BL/6 mouse model of dextran sulfate (DSS)-induced acute ulcerative colitis (UC). Treatment with C. butyricum and/or COS ameliorated UC symptoms in vivo, and the strongest eff...

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Detalles Bibliográficos
Autores principales: Huang, Xingxi, Hu, Jutuan, Zhang, Heng, Li, Ji, Zhu, Xi, Liu, Yangyang, Liang, Yunxiang, Mei, Yuxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10100383/
https://www.ncbi.nlm.nih.gov/pubmed/36975838
http://dx.doi.org/10.1128/spectrum.04370-22