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Immunopathology of terminal complement activation and complement C5 blockade creating a pro‐survival and organ‐protective phenotype in trauma
BACKGROUND AND PURPOSE: Traumatic haemorrhage (TH) is the leading cause of potentially preventable deaths that occur during the prehospital phase of care. No effective pharmacological therapeutics are available for critical TH patients yet. Here, we identify terminal complement activation (TCA) as a...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10100417/ https://www.ncbi.nlm.nih.gov/pubmed/36251578 http://dx.doi.org/10.1111/bph.15970 |