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Improving mitotic cell counting accuracy and efficiency using phosphohistone‐H3 (PHH3) antibody counterstained with haematoxylin and eosin as part of breast cancer grading

BACKGROUND: Mitotic count in breast cancer is an important prognostic marker. Unfortunately, substantial inter‐ and intraobserver variation exists when pathologists manually count mitotic figures. To alleviate this problem, we developed a new technique incorporating both haematoxylin and eosin (H&am...

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Detalles Bibliográficos
Autores principales: Ibrahim, Asmaa, Toss, Michael S., Makhlouf, Shorouk, Miligy, Islam M., Minhas, Fayyaz, Rakha, Emad A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10100421/
https://www.ncbi.nlm.nih.gov/pubmed/36349500
http://dx.doi.org/10.1111/his.14837