Comprehensive investigation of a structural variant in a bi‐specific, N‐and C‐terminal Fc‐fusion molecule, and its monitoring with LC‐MS based method

There is an increasing interest in the generation of Fc‐fusion molecules to exploit the effector functions of Fc and the fusion partner, towards improving the therapeutic potential. The Fc‐fusion molecules have unique structural and functional attributes that impart various advantages. However, the...

Descripción completa

Detalles Bibliográficos
Autores principales: Datola, Antonio, Satwekar, Abhijeet, Barron, Nadine, DeRosa, Sawako, Tomascak, Brittany, Dawson, Jessica, Palmese, Angelo, Rossi, Mara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
ARTICLES
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10100451/
https://www.ncbi.nlm.nih.gov/pubmed/36333865
http://dx.doi.org/10.1002/bit.28281

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10100451/
https://www.ncbi.nlm.nih.gov/pubmed/36333865
http://dx.doi.org/10.1002/bit.28281

Ejemplares similares