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Comprehensive investigation of a structural variant in a bi‐specific, N‐and C‐terminal Fc‐fusion molecule, and its monitoring with LC‐MS based method
There is an increasing interest in the generation of Fc‐fusion molecules to exploit the effector functions of Fc and the fusion partner, towards improving the therapeutic potential. The Fc‐fusion molecules have unique structural and functional attributes that impart various advantages. However, the...
Autores principales: | Datola, Antonio, Satwekar, Abhijeet, Barron, Nadine, DeRosa, Sawako, Tomascak, Brittany, Dawson, Jessica, Palmese, Angelo, Rossi, Mara |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10100451/ https://www.ncbi.nlm.nih.gov/pubmed/36333865 http://dx.doi.org/10.1002/bit.28281 |
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