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Lysosomal Targeting of β‐Cyclodextrin

β‐Cyclodextrin (β‐CD) and derivatives are approved therapeutics in >30 clinical settings. β‐CDs have also shown promise as therapeutics for treatment of some lysosomal storage disorders, such as Niemann‐Pick disease type C, and other disease states which involve metabolite accumulation in the lys...

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Detalles Bibliográficos
Autores principales: Mascherpa, Andrea, Ishii, Nozomii, Tayagui, Ayelen, Liu, Jiang, Sollogoub, Matthieu, Fairbanks, Antony J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10100462/
https://www.ncbi.nlm.nih.gov/pubmed/36265126
http://dx.doi.org/10.1002/chem.202203252