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Hapten-Decorated DNA Nanostructures Decipher the Antigen-Mediated Spatial Organization of Antibodies Involved in Mast Cell Activation

[Image: see text] The immunological response of mast cells is controlled by the multivalent binding of antigens to immunoglobulin E (IgE) antibodies bound to the high-affinity receptor FcεRI on the cell membrane surface. However, the spatial organization of antigen–antibody–receptor complexes at the...

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Detalles Bibliográficos
Autores principales: Schneider, Leonie, Rabe, Kersten S., Domínguez, Carmen M., Niemeyer, Christof M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10100567/
https://www.ncbi.nlm.nih.gov/pubmed/36990450
http://dx.doi.org/10.1021/acsnano.2c12647