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Machine Learning Prediction and Phyloanatomic Modeling of Viral Neuroadaptive Signatures in the Macaque Model of HIV-Mediated Neuropathology

In human immunodeficiency virus (HIV) infection, virus replication in and adaptation to the central nervous system (CNS) can result in neurocognitive deficits in approximately 25% of patients with unsuppressed viremia. While no single viral mutation can be agreed upon as distinguishing the neuroadap...

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Detalles Bibliográficos
Autores principales: Ramirez-Mata, Andrea S., Ostrov, David, Salemi, Marco, Marini, Simone, Magalis, Brittany Rife
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10100676/
https://www.ncbi.nlm.nih.gov/pubmed/36847516
http://dx.doi.org/10.1128/spectrum.03086-22